James Hird (ribs) and Scott Lucas (hamstring) have both come out of the side that defeated Richmond last week by 78-points. Mark Alvey is the other omission, who has been sidelined with a bout of the flu.
In his 100th game Adam Ramanauskas has been named in the centre alongside Dean Solomon and Joe Misiti.
The team traveled to Perth last night in preparation for the match. The squad had a light training session this morning at the beach and will spend time at Subiaco this afternoon walking around the ground.
Essendon team:
B: McVeigh, Fletcher, Richards
HB: Welsh, Bolton, Bradley
C: Solomon, Misiti, Ramanauskas
HF: J.Johnson, McPhee, Haynes
F: Murphy, Lloyd, Lovett-Murray
R: Allan, M.Johnson, Peverill
Int: Hille, Stanton, Dyson, Bullen
Emerg: Alvey, Mercuri, Winderlich
In: Bolton, Fletcher, Stanton
Out: Hird (ribs), Lucas (hamstring), Alvey (flu)